Higher Renal Replacement Therapy Dose Delivery Influences on Drug Therapy
نویسندگان
چکیده
منابع مشابه
Higher renal replacement therapy dose delivery influences on drug therapy.
Higher doses of renal replacement therapy have profound effects on pharmacotherapy, yet little research has been conducted in this area. High-volume renal replacement therapies influence both the pharmacokinetic and the pharmacodynamic profiles of all drugs administered to these critically ill patients. Intermittent high-dose "hybrid" hemodialysis therapies remove drugs to a much different degr...
متن کاملFemoral Access and Delivery of Continuous Renal Replacement Therapy Dose.
AIMS The study aims to describe the use of dialysis catheters in critically ill patients treated with continuous renal replacement therapy (CRRT) and to study the impact of femoral versus non-femoral access on CRRT dose. METHODS Statistical analysis and predictive modelling of data from the Randomized Evaluation of Normal vs. Augmented Level renal replacement therapy trial. RESULTS The femo...
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Continuous renal replacement therapy (CRRT) has given clinicians an important option in the care of critically ill patients. The slow and continuous dialysate and ultrafiltrate flow rates that are employed with CRRT can yield drug clearances similar to an analogous glomerular filtration rate of the native kidneys. Advantages such as superior volume control, excellent metabolic control, and hemo...
متن کاملHigher colistin dose during continuous renal replacement therapy: look before leaping!
We read with great interest the comments of Rocco and colleagues on colistin dosing in a recent letter in Critical Care [1]. The application of continuous renal replacement therapy (CRRT) indeed offers an opportunity to prescribe very high colistin doses without exposing the patient to excess toxicity [2]. However, caution is needed before implementing this so-called CRRT ‘shield’ function. Fir...
متن کاملContinuous renal replacement therapy.
Acute renal failure refers to sudden deterioration in biochemical and physiological functioning of kidneys and often associated with multi organ failure. Continuous renal replacement therapy (CRRT) holds special significance for the treatment of renal failure due to a variety of factors. It is believed that CRRT helps in restoration of acid-base imbalances and electrolyte abnormalities. Along w...
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ژورنال
عنوان ژورنال: Artificial Organs
سال: 2003
ISSN: 0160-564X,1525-1594
DOI: 10.1046/j.1525-1594.2003.07283.x